Week 2 NFL Odds

The Week 2 NFL odds for the 2020 regular season are here, and BetRivers.com has over 200 different bettings options for each Week 2 NFL matchup.

The first week of the season set the tempo but didn’t reveal too much about betting trends and team progression. Bettors and bookmakers alike are trying to get a pulse of the 2020 NFL regular-season, which should make for some interesting lines the next few weeks.

Rob Dauster is here to break down the bets that are intriguing to him and highlights betting trends that can help you make the right call.

So let’s dive into it and bet on NFL:

Sunday Week 2 NFL Odds:

1:00 p.m.: 49ers (-205 ML) at Jets (+260 ML). San Francisco -7. O/U 42.5
1:00 p.m.: Rams (-114) at Eagles (+100). Los Angeles -1. O/U 45.5
1:00 p.m.: Giants (+200) at Bears (-235). Chicago -5.5. O/U 42.5
1:00 p.m.: Panthers (+350) at Buccaneers (-420). Tampa Bay -9.5. O/U 42.5
1:00 p.m.: Broncos (+300) at Steelers (-360). Pittsburgh -7.5. O/U 41.5
1:00 p.m.: Jaguars (+310) at Titans (-275). Tennessee -9. O/U 42.
1:00 p.m.: Lions (+225) at Packers (-265). Green Bay -6.5. O/U 49.5
1:00 p.m.: Vikings (+138) at Colts (-157). Indianapolis -3. O/U 48
1:00 p.m.: Bills (-235) at Dolphins (+200). Buffalo -5.5. O/U 41
1:00 p.m.: Falcons (+175) at Cowboys (-200). Dallas -4.5. O/U 53
4:05 p.m.: Washington (+240) at Cardinals (-278). Arizona -4.5. O/U 46.5
4:25 p.m.: Chiefs (-275) at Chargers (+310). Kansas City -8.5. O/U 47.5
4:25 p.m.: Ravens (-335) at Texans (+285). Baltimore -7. O/U 52
8:20 p.m.: Patriots (+165) at Seahawks (-190). Seattle -4. O/U 45.

MORE: How to Bet on Football


  • 1:00 p.m. ET: FOX.
  • Moneyline: Bears -235, Giants +200
  • Spread: Bears -5.5
  • Over/Under: 42 points
  • Implied Score: Bears 23.75, Giants 18.25

The Giants are easily my favorite play of the weekend, and it’s really not close. 

I am not a believer in the Bears, or in Mitch Trubisky. They were down 23-6 against the Lions in Week 1 late in the second, when Trubisky led a comeback against a Lions team that A) was without their top three corners due to injury and Jamie Collins due to an ejection, and B) is still the Detroit Lions. And Chicago still needed D’Andre Swift to drop a wide-open, game-winning touchdown pass with six seconds left to win. 

There’s also the matter of Allen Robinson, who may or may not be disgruntled and want out of Chicago. That would make things more challenging for the Bears offense but would also provide Anthony Miller, Ted Ginn, and Jimmy Graham more scoring opportunities. Miller is +275 to score a TD, which is worth watching given Trubisky’s late-game hookup with Miller in Week 1 that won the game for Chicago.

New York, on the other hand, did not look awful against a Pittsburgh team that is much better than people realize. If it wasn’t for a couple of horrid Danny Dimes interceptions — one came with New York at the goal line, the other set Pittsburgh up with a short field for their first touchdown — the Giants might have actually had a shot to win that game. 

And the Bears are not the Steelers.

Any time the process leads you to a place where you can fade Mitch Trubisky, you do it. After all, only 63% of ML bets are on Bears -235.


  • 1:00 p.m. ET: FOX.
  • Moneyline: Packers (-265), Lions (+225)
  • Spread: Packers -6.5
  • Over/Under: 49.5 points
  • Implied Score: Packers 28, Lions 21.5

Let’s use some of the same logic as before. The Lions have a banged-up secondary that allowed Mitch freakin’ Trubisky to march down the field against them three times in the final 20 minutes of a game they led at home by 17 points.

And now we’re asking them to go into Lambeau Field and try to slow down the Packers and Aaron Rodgers, who dropped a 32/44-364-4 line on the Vikings in Minneapolis en route to putting up 43 points? That might be the reason 94% of the public is on Packers -245 ML and 89% of the public is on Packers -6.5.

Keep an eye on the injuries here, Jeff Okudah and Kenny Golladay specifically with Desmond Trufant looking likely to play. But even with all three healthy and on the field, I like the Pack in this spot. 


  • 4:25 p.m. ET: CBS.
  • Moneyline: Chargers (+310), Chiefs (-375)
  • Spread: Chiefs (-8.5)
  • Over/Under: 47.5 points
  • Implied Score: Chiefs 28, Chargers 19.5

I know this is going to sound crazy, but I like the Chargers in this spot.

For starters, they are a home underdog playing a division game and getting more than a touchdown. Those are the spots that we should be targeting, as those are the games that tend to be dogfights. 

But the matchup makes sense as well. The way that you beat the Chiefs — or, at the very least, slow them down — is by running the ball. They’re susceptible on the ground, and that’s precisely the style that Anthony Lynn wants to play.

And it’s worth noting that the Chargers have been pretty good at slowing down Patrick Mahomes in the past. In two games against the best QB in the NFL last season, San Diego held him to 35-57 passing and a combined 356 yards and two TDs. 

Using that same logic, I also like the under here. I don’t expect Tyrod Taylor to suddenly become an explosive quarterback, I just think that he’ll find a way to drain clock and keep the Chargers close.